By Carmen Splane, Contributor

Anne Hathaway and Jake Gyllenhaal get a second chance to be on-screen lovers in a film that has been earning the dynamic duo rave reviews for their portrayals. “Love and Other Drugs” reunites the “Brokeback Mountain” stars, but gives them a decidedly more lighthearted script to work with this time around.

The romantic comedy is an adaptation of Jaime Reidy’s memoir, “Hard Sell: The Evolution of a Viagra Salesman.” Reidy penned his own memoir detailing his experiences as a never-do-well slacker who took advantage of his bosses in the pharmaceutical industry. Reidy turned himself into a top-selling sales rep in the ‘90s by getting doctors to sign undated sample receipts, thus cheating his way through the system. Once his cover was blown and he was fired, Reidy’s book was published.

“Love and Other Drugs” is a retelling of this story with the addition of an on-screen love affair. Hathaway and Gyllenhaal play out the typical rom-com scenario: Boy and girl aren’t looking for love, boy and girl find each other, boy and girl fall madly, hopelessly and unrealistically in love. The film chronicles their unlikely relationship and the career of Gyllenhaal’s Jamie Randall, who is trying to make it big in the male enhancement market of pharmaceuticals.

Gyllenhaal walks into what is usually more comfortable territory for Hathaway. Known mostly for hard-hitting dramas and thrillers, Gyllenhaal is tapping into the market of romantic comedies for the first time since 2001’s “Bubble Boy.” From what critics are saying, this departure from the norm is stirring up talks of a Best Actor nomination.

Movie: Love and Other Drugs

Directed by: Edward Zwick

Release Date: Nov. 24

Starring: Jake Gyllenhaal, Anne Hathaway